Therapeutic antibodies have a number of essential mechanisms of action (MOAs), one of which is antibody-dependent cell-mediated phagocytosis (ADCP). Monocytes, macrophages, neutrophils, and dendritic cells can all mediate ADCP in vivo via FcyRIIa, FcyRI, and FcyRIIIa. According to its method, antibodies attach their homologous antigens to their target cells via their antigen recognition domains, and […]
